It's only Week 3, and injuries are already changing the landscape. More information is available each week, and I'm consolidating the data to help you make good DFS choices with my Week 3 DraftKings NFL DFS plays, including my top stack, value picks, and GPP plays.

Our NFL DFS Projections and DFS Pick'em Tool are also great resources; if you're interested in college DFS, we have projections here too.

Top Stack:

San Francisco 49ers

The injury bug has bitten a considerable portion of the league to start the year, and one team that is getting hit especially hard is the 49ers. They have been without Christian McCaffrey and just lost Deebo Samuel for a handful of weeks. To add to those blows, Kittle may have some injuries to sort through after a mid-week downgrade. Still, they are scoring 24.50 points per game, along with a healthy team total of 25.50 points, which tells us that the missing stars will likely lead to massive upside in a condensed target tree.

For reference, here is how the models at PayDirt view the best QB+2 stacks on the slate:

A screenshot of a computer Description automatically generated

While the 49ers are not the top overall QB+2 available, they are right in the mix, with a top median of 49.76 points from Purdy-Aiyuk-Kittle. Their top finish rate is the second best in the simulations at 9.60%, and all of that comes at a relatively low price of just $17,900 on DraftKings. The only downside to using an SF stack this week is it doesn't play well with Jordan Mason as an RB option (big negative correlations there). However, a bevy of RB options at lower ownership can compensate for the value you miss out on without Mason in your lineup.

The 49ers make for an excellent stack in terms of value, upside, and direct leverage on Mason in large-field GPPs. They should be where you start your builds if you are hand-building.

Top Value Plays

RB: Jordan Mason

There is little to say here, as Jordan Mason is painfully mispriced. He is projected for 19.13 fantasy points with a ceiling of 35.31, the second-highest mark at RB on the slate, and he is only $6,200. His utilization score for the year is 8.21, typically worth 16.30 PPR points per game, which would still have him as underpriced. He's an awesome play, and even if he is 40% owned, that's probably still too low. Plug and play, move along.

WR: Brandon Aiyuk

Without Deebo Samuel or Christian McCaffrey, we can expect Aiyuk to be the focal point of the 49ers' offense. He's been underwhelming to start the year with just a 14% target share and 17% of the air yards, but his ceiling can touch a 25/35 split of those numbers based on his historical output. Last week, he went from 79% route participation in Week 1 to 93% in Week 2. He currently projects for 17.64 PPR points and a 21.10% rate of hitting 4x his salary based on the simulations at PayDirt. He's a terrific play as part of a stack or as a one-off.

TE: Dallas Goedert

It may seem strange that a $4,600 TE is a "value," but Goedert projects as such and is getting hardly any ownership. We are seeing the same situation week after week—A TE with elite upside priced in the mid-4k range at a $1k discount. We also saw a meaningful role change last week when A.J. Brown wasn't available. Goedert went from 77% route participation in Week 1 to 100% in Week 2 and 1% of the air yards in Week 1 to 18% last week. His projection-ceiling combo of 11.77/25.22 is respectable and likely undercuts his upside based on the role change and increased opportunity. He's an excellent pairing with Jalen Hurts as a QB+1.

Top GPP Plays

RB: Aaron Jones

It would be easy enough for me to put Jordan Mason in this spot as well, but in the interest of relative value, I'm going with Aaron Jones. He projects for only 5% ownership at the time of writing and has a median projection of 14.82 PPR fantasy points. What I like about him is his usage. A utilization score of 7.51 gives him an expectation of 14.10 PPR points, and he has been unlucky, as evidenced by his expected fantasy points of 19.14 per game being higher than his actual output of 15.35 points. The offensive environment is strong against Houston, and his price leaves upside on the table. At his ownership, he's a terrific play in larger field GPPs.

WR: Davante Adams

Davante Adams, currently projected for just 3% owned, gets about the best matchup possible against the lowly Carolina Panthers. So far, he has the second-best utilization score among all WRs at 9.28, which is good for an expectation of 21.30 PPR points. According to the simulations over at PayDirt, he hits 20+ PPR points 31.50% of the time. He's the baseline definition of a high-end GPP option at an accessible price point.

TE: Trey McBride

Even though he's the most expensive TE on the slate, Trey McBride still makes a lot of sense, given the roster construction that remains available after spending on him. A handful of cheaper QBs and mid- to low-priced RBs are available, making spending on WR and TE positions easy. Pair that information with a strong offensive environment with Arizona playing Detroit, and McBride is a perfect option in GPPs. The top-rated TE projects for 14.03 with a ceiling of 30.42 and is only looking at 5% ownership right now. With people wanting to jam in George Kittle (projected for 37% ownership), a simple pivot to McBride as a one-off gives you a massive amount of relative value on the field. He makes for an ideal large-field GPP option for those who want to gain leverage on chalky San Francisco stacks.